The neuronal centrosome as a generator of microtubules for the axon.

I . Introduction 11. Evidence of a Centrosomal Origin for Axonal Microtubules A. Axonal Microtubules Do Not Originate within the Axon B. Nucleation and Release of Microtubules from the Neuronal Centrosome C. Inhibition of Microtubule Nucleation at the Centrosome Compromises Axon Growth D. Centrosomal Microtubules Are Transported into the Axon Ill. Implications of a Centrosomal Origin for Axonal Microtubules A. Microtubule Nucleation and Release from the Centrosome of Neurons and Nonneuronal Cells B . Microtubule Translocation from the Centrosome C. Regulation of Microtubule Nucleation and Release from the Neuronal Centrosome D. Mechanisms for Elaborating the Axonal Microtubule Array